Katrina Lexa became interested in computational chemistry as an undergraduate at Hamilton College, working with Prof. George C. Shields. She received her PhD in Medicinal Chemistry from the University of Michigan with Prof. Heather Carlson, then went on to perform postdoctoral research with Prof. Matt Jacobson at the University of California San Francisco supported by an NIH Ruth L. Kirschstein Individual National Research Service Award. After her postdoc, Katrina joined Merck as a modeler within the new Chemical Biotechnology department. As part of Modeling and Informatics, Katrina’s research centered around structure and ligand-based design in Process and Discovery Chemistry.
In 2017, Katrina joined Denali Therapeutics, where she contributes to efforts to develop breakthrough therapies for neurodegenerative diseases through the application of modeling and informatics.